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MK-4541 

Cat. No. M30623

All AbMole products are for research use only, cannot be used for human consumption.

MK-4541  Structure

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Quality Control & Documentation
Biological Activity

MK-4541 is an orally active and selective androgen receptor (AR) modulator. MK-4541 acts as an antagonist to inhibit 5α-reductase. MK-4541 inhibits proliferation and induces apoptosis in AR positive prostate cancer cells. MK-4541 significantly inhibited the growth of R3327-G prostate tumors in xenograft mouse model.

Chemical Information
Molecular Weight 428.49
Formula C22H31F3N2O3
CAS Number 796885-38-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Michael J Chisamore, et al. J Steroid Biochem Mol Biol. A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice

[2] Azriel Schmidt, et al. J Steroid Biochem Mol Biol. Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: MK-4541  supplier, Androgen Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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