Free shipping on all orders over $ 500

MitoSOX Red Mitochondrial Superoxide Indicator

Cat. No. M19992
MitoSOX Red Mitochondrial Superoxide Indicator Structure
Size Price Availability Quantity
50ug USD 140  USD175 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity N/A
  • COA
  • MSDS
Biological Activity

The MitoSOX Red Mitochondrial Superoxide Indicator, a cationic derivative of dihydroethidium, is designed to detect Mitochondrial Superoxide in living cells with high specificity. It is a new type of fluorescent probe specifically targeting live cell line sites. It has membrane permeability and can bind mitochondria quickly and selectively. Once entering mitochondria, it is oxidized by superoxide and binds to nucleic acid to produce strong red fluorescence. Its maximum excitation/emission wavelength is 510/580nm.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 759.71
Formula C43H43N3IP
CAS Number
Purity N/A
Solubility DMSO:5mM
Storage -20°C , protect from light , dry , sealed
Related Fluorescent Dye Products
Lyso-Tracker Red

Lyso-Tracker Red is an eosinophilic fluorescent probe with a maximum excitation wavelength of 577nm and a maximum emission wavelength of 590nm. Lyso-Tracker Red must be at very low concentrations (usually about 50nM) to achieve excellent selectivity.

FITC-Dextran (MW 10000)

FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm).

ICG-OSu

ICG-OSu (ICG NHS ester) is a near infrared fluorescent agent with amine reactivity that is widely used in the design of in vivo imaging probes. Em >750 nm infrared, Ex >750 nm infrared.

FITC-Dextran(MW 40000)

FITC-Dextran is a marker consisting of coupling fluorescein-isothiocyanate to dextran.

Cyanine 5 maleimide

Cy5 maleimide is a fluorescent dye and various cyanidin 5 (Cy5) dyes have been used to label biomolecules for fluorescent imaging and other fluorescence-based biochemical analyses. They are widely used to label peptides, proteins, and oligonucleotides, among others. The maximum excitation/emission wavelength is 651/670 nm.

  Catalog
Abmole Inhibitor Catalog




Keywords: MitoSOX Red Mitochondrial Superoxide Indicator supplier, Fluorescent Dye, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.