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MitoSOX Red

Cat. No. M19992

All AbMole products are for research use only, cannot be used for human consumption.

MitoSOX Red Structure
Synonym:

Mitochondrial Superoxide Indicator

Size Price Availability Quantity
50ug USD 120  USD120 In stock
500ug USD 330  USD330 In stock
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Quality Control & Documentation
  • Purity: Biological stain
  • COA
  • MSDS
Biological Activity

The MitoSOX Red (Mitochondrial Superoxide Indicator), a cationic derivative of dihydroethidium, is designed to detect Mitochondrial Superoxide in living cells with high specificity. It is a new type of fluorescent probe specifically targeting live cell line sites. It has membrane permeability and can bind mitochondria quickly and selectively. Once entering mitochondria, it is oxidized by superoxide and binds to nucleic acid to produce strong red fluorescence. Its maximum excitation/emission wavelength is 510/580nm.

Product Citations
Chemical Information
Molecular Weight 759.70
Formula C43H43IN3P
CAS Number 1003197-00-9
Solubility (25°C) DMSO 60 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Xingtao Zhao, et al. Oxid Med Cell Longev. Quercetin Protects Ethanol-Induced Hepatocyte Pyroptosis via Scavenging Mitochondrial ROS and Promoting PGC-1 α-Regulated Mitochondrial Homeostasis in L02 Cells

[2] Yuta Kashiwagi, et al. Exp Neurol. Mitochondrial biogenesis factor PGC-1α suppresses spinal morphine tolerance by reducing mitochondrial superoxide

[3] Baofeng Chen, et al. Arthritis Res Ther. Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage

[4] Aleksandra Wojtala, et al. Methods Enzymol. Methods to monitor ROS production by fluorescence microscopy and fluorometry

[5] Jacek Zielonka, et al. Free Radic Biol Med. Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth

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Keywords: MitoSOX Red, Mitochondrial Superoxide Indicator supplier, Fluorescent Dye, inhibitors, activators

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