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Methyl β-D-Galactopyranoside

Cat. No. M20007
Methyl β-D-Galactopyranoside Structure
Synonym:

Methylgalactoside

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500mg USD 50  USD50 In stock
1g USD 80  USD80 In stock
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Biological Activity

Methyl Β-D-galactopyranoside (Methyl β-D-Galactopyranoside ) is an endogenous metabolite. Inside cells, methyl-Β-D-galactopyranoside is mainly located in the cytoplasm. Outside the human body, methyl-Β-D-galactopyranoside can be found in cereals and cereal products.

Chemical Information
Molecular Weight 194.18
Formula C7H14O6
CAS Number 1824-94-8
Solubility (25°C) Water ≥ 200 mg/mL
Storage 2-8°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Md R Amin, et al. Glycoconj J. Methyl β-D-galactopyranoside esters as potential inhibitors for SARS-CoV-2 protease enzyme: synthesis, antimicrobial, PASS, molecular docking, molecular dynamics simulations and quantum computations

[2] Md Ruhul Amin, et al. Molecules. Synthesis, Antimicrobial, Anticancer, PASS, Molecular Docking, Molecular Dynamic Simulations & Pharmacokinetic Predictions of Some Methyl β-D-Galactopyranoside Analogs

[3] Fazle Rabbi Shakil Ahmed, et al. Int J Biol Macromol. Antitumor properties of a methyl-β-d-galactopyranoside specific lectin from Kaempferia rotunda against Ehrlich ascites carcinoma cells

[4] N Sekkal, et al. Spectrochim Acta A Mol Biomol Spectrosc. Harmonic dynamics of alpha- and beta-methyl-D-galactopyranoside in the crystalline state

[5] P Kovc, et al. Carbohydr Res. Synthesis and characterization of methyl 6-O-alpha- and -beta-D-galactopyranosyl-beta-D-galactopyranoside

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Keywords: Methyl β-D-Galactopyranoside , Methylgalactoside supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

 
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