MEK-IN-4 is a MEK inhibitor. MEK-IN-4 can be used for the research of inflammatory disorders and cancers.
| Molecular Weight | 374.46 |
| Formula | C21H18N4OS |
| CAS Number | 297744-42-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related MEK Products |
|---|
| Glycinexylidide
Glycinexylidide (GX) is the active metabolite of Lidocaine. |
| Xantocillin
Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway. |
| MEK-IN-6 hydrate
MEK-IN-6 hydrate is a MEK inhibitor. |
| MS934
MS934 is a novel improved VHL-recruiting MEK 1/2 degrader. |
| Nedometinib
Nedometinib is a tyrosine kinase inhibitor targeting to MEK1. |
Products are for research use only. Not for human use. We do not sell to patients.
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