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Mag-Fluo-4 AM

Cat. No. M31282

All AbMole products are for research use only, cannot be used for human consumption.

Mag-Fluo-4 AM Structure
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50ug USD 225  USD225 In stock
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Quality Control & Documentation
Biological Activity

Mag-Fluo-4 AM is a fluorescent chelator for Ca2+ with high affinity for calcium and can specifically recognize intracellular calcium ions with high sensitivity and low cytotoxicity. Addition of AM acetylmethyl ester allows better access to the cell, and after being sheared by the intracellular esterase, it stays in the cell and binds to calcium ions, thus generating strong fluorescence (λex=475 nm, λem=515 nm).

Chemical Information
Molecular Weight 817.65
Formula C37H33F2NO18
CAS Number 1097709-31-3
Form Oil
Storage -20°C, protect from light
References

[1] Hao Zhao, et al. Eur J Pharmacol. Cisplatin induces damage of auditory cells: Possible relation with dynamic variation in calcium homeostasis and responding channels

[2] Andrés F Milán, et al. Biochim Biophys Acta Gen Subj. Calibration of mammalian skeletal muscle Ca2+ transients recorded with the fast Ca2+ dye Mag-Fluo-4

[3] Ana M Rossi, et al. Cell Calcium. Reliable measurement of free Ca2+ concentrations in the ER lumen using Mag-Fluo-4

[4] J Fernando Olivera, et al. J Muscle Res Cell Motil. A study of the mechanisms of excitation-contraction coupling in frog skeletal muscle based on measurements of [Ca2+] transients inside the sarcoplasmic reticulum

[5] Stephen Hollingworth, et al. J Physiol. Measurement and simulation of myoplasmic calcium transients in mouse slow-twitch muscle fibres

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Keywords: Mag-Fluo-4 AM supplier, Fluorescent Dye, inhibitors, activators

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