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Ly93 

Cat. No. M28984

All AbMole products are for research use only, cannot be used for human consumption.

Ly93  Structure

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Quality Control & Documentation
Biological Activity

Ly93 is a selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with an IC50 of 91 nM.

Chemical Information
Molecular Weight 332.4
Formula C21H20N2O2
CAS Number 1883528-69-5
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Feng Hua, et al. Neural Regen Res. Substance P promotes epidural fibrosis via induction of type 2 macrophages

[2] Yutong Huang, et al. Pharmazie. A selective sphingomyelin synthase 2 inhibitor ameliorates diet induced insulin resistance via the IRS-1/Akt/GSK-3β signaling pathway

[3] Yali Li, et al. Eur J Med Chem. Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ly93  supplier, inhibitors, activators

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