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LY2922470

Cat. No. M10851

All AbMole products are for research use only, cannot be used for human consumption.

LY2922470  Structure

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Quality Control & Documentation
Biological Activity

LY2922470 is an effective, selective, orally potent GPR40 agonist that acts on human GPR40, mouse GPR40, and rat GPR40 EC50 The values are 7 nM, 1 nM, and 3 nM, respectively. LY2922470 lowers blood glucose levels while significantly increasing insulin and GLP-1, potentially for use in the study of type 2 diabetes mellitus (T2DM).

Chemical Information
Molecular Weight 475.6
Formula C28H29NO4S
CAS Number 1423018-12-5
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage 4°C,protect from light ,dry ,sealed
References

[1] Joo Won Kim, et al. Diabetes Metab J. GPR40 Agonism Modulates Inflammatory Reactions in Vascular Endothelial Cells

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