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Lutikizumab (ABT-981) is an anti-IL-1α and IL-1β dual variable domain immunoglobulin. Lutikizumab binds and inhibits IL-1α and IL-1β. Lutikizumab can be used for the research of osteoarthritis.
CAS Number | 1791411-57-8 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Perfluorodecanoic acid
Perfluorodecanoic acid (PFDA) is widely used as surfactants, polymer and plastic additives, wetting agents, corrosion inhibitors, lubricants, foam-fire extinguishants, etc. Perfluorodecanoic acid induces weight loss and increases liver weight and lipid content in mice. Perfluorodecanoic acid also reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver. |
IL-15-IN-1
IL-15-IN-1 is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM. |
IL-17 modulator 3
IL-17 modulator 3 is an IL-17 modulator. |
IL-17 modulator 4
IL-17 modulator 4 is a proagent of IL-17 modulator 1. |
IL-17A modulator-3
IL-17A modulator-3 is a IL-17A modulator. |
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