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Lixisenatide acetate

Cat. No. M13970
Lixisenatide acetate Structure
Size Price Availability Quantity
1mg USD 150  USD150 In stock
5mg USD 290  USD290 In stock
10mg USD 480  USD480 In stock
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Quality Control & Documentation
Biological Activity

Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).

Chemical Information
Molecular Weight 5218.79
CAS Number 1997361-87-1
Solubility (25°C) Water 50 mg/mL
Storage -20°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Daniel A Hussar. NewDrugs 2017, part 2

[2] Daniel A Hussar, et al. 2017 New Drug Update

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Keywords: Lixisenatide acetate supplier, GLP Receptor, inhibitors, activators

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