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LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism.
| Molecular Weight | 645.7 |
| Formula | C30H34F3N7O4S |
| CAS Number | 2245072-21-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
| Related Oxytocin Receptor Products |
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| [Asp5]-Oxytocin
[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. |
| (d(CH2)51, Tyr(Me)2, Thr4, Orn8, Tyr-NH29)-Vasotocin
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior. |
| (d(CH2)51, Tyr(Me)2, Orn8)-Oxytocin
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. |
| (Val3, Pro8)-Oxytocin
(Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist. |
| (d(CH2)51, Tyr(Me)2, Thr4, Orn8, des-Gly-NH29)-Vasotocin
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons. |
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