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LDC000067 reduces Ser2-P, induces p53 activation and leads to apoptosis in mESCs. In addition, LDC067 also dose-dependently inhibits P-TEFb-dependent de novo RNA synthesis of cellular genes.
| Molecular Weight | 370.43 |
| Formula | C18H18N4O3S |
| CAS Number | 1073485-20-7 |
| Solubility (25°C) | 64 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| ML 315
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