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LAP

Cat. No. M6892

All AbMole products are for research use only, cannot be used for human consumption.

LAP Structure
Size Price Availability Quantity
100mg USD 40  USD40 In stock
250mg USD 70  USD70 In stock
500mg USD 100  USD100 In stock
1g USD 140  USD140 In stock
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Quality Control & Documentation
Biological Activity

LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a water soluble, cytocompatible, Type I photoinitiator for use in the polymerization of hydrogels or other polymeric materials. This photoinitator is preferred over Irgacure 2959 for biological applications due to its increased water solubility, increased polymerization rates with 365 nm light, and absorbance at 400 nm allowing for polymerization with visible light. The improved polymerization kinetics enable cell encapsualation at reduced initiator concentration and longer wavelength light, which has been shown to reduce initiator toxicity and increase cell viability.

Chemical Information
Molecular Weight 294.21
Formula C16H16LiO3P
CAS Number 85073-19-4
Solubility (25°C) DMSO 15 mg/mL
Water 6 mg/mL
Storage 4°C, protect from light, dry
References

[1] Heqi Xu, et al. Biomed Mater. Effects of Irgacure 2959 and lithium phenyl-2,4,6-trimethylbenzoylphosphinate on cell viability, physical properties, and microstructure in 3D bioprinting of vascular-like constructs

[2] Alexander K Nguyen, et al. Biointerphases. Toxicity and photosensitizing assessment of gelatin methacryloyl-based hydrogels photoinitiated with lithium phenyl-2,4,6-trimethylbenzoylphosphinate in human primary renal proximal tubule epithelial cells

[3] Muro, et al. J Med Chem. Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist.

[4] Benjamin D Fairbanks, et al. Biomaterials. Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility

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Keywords: LAP supplier, inhibitors, activators

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