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Labetuzumab

Cat. No. M24980

All AbMole products are for research use only, cannot be used for human consumption.

Labetuzumab Structure
Size Price Availability Quantity
100ug USD 220  USD220 In stock
1mg USD 440  USD440 In stock
5mg USD 880  USD880 In stock
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Quality Control & Documentation
Biological Activity

Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy.

Immobilized human CEACAM5 at 2 ug/mL can bind labetuzumab, EC50=0.009815 ug/mL.

Chemical Information
CAS Number 219649-07-7
Storage Store at ≤ -20℃ for 24 months. Avoid repeated freeze-thaw cycles.
References

[1] Diana C DeLucia, et al. Clin Cancer Res. Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drυg Conjugate in Neuroendocrine Prostate Cancer

[2] Wenjuan Dong, et al. Eur J Med Chem. Antibody-drυg conjugates of 7-ethyl-10-hydroxycamptothecin: Sacituzumab govitecan and labetuzumab govitecan

[3] Robert M Sharkey, et al. Mol Cancer Ther. Selective and Concentrated Accretion of SN-38 with a CEACAM5-Targeting Antibody-Drυg Conjugate (ADC), Labetuzumab Govitecan (IMMU-130)

[4] Manjulika Das. Lancet Oncol. Labetuzumab govitecan in metastatic colorectal cancer

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Keywords: Labetuzumab supplier, inhibitors, activators

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