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L-Selenocystine

Cat. No. M39833

All AbMole products are for research use only, cannot be used for human consumption.

L-Selenocystine Structure

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Quality Control & Documentation
Biological Activity

L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.

Chemical Information
Molecular Weight 334.09
Formula C6H12N2O4Se2
CAS Number 29621-88-3
Form Solid
Solubility (25°C) Water 5 mg/mL (ultrasonic and warming and adjust pH to 1 with HCl)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wei-Lun Hsu et al. Cell Death Dis. Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through p62-Keap-1-Nrf2 axis

[2] Xin Wen et al. Small. Selenocystine and Photo-Irradiation Directed Growth of Helically Grooved Gold Nanoarrows

[3] Yinhong Xie et al. Colloids Surf B Biointerfaces. Selective endothelialization and alleviation of neointimal hyperplasia by functionalizing the Ti-O surface with l-selenocystine and KREDVC

[4] Kandhan Satheeshkumar et al. Chemistry. Reactivity of Selenocystine and Tellurocystine: Structure and Antioxidant Activity of the Derivatives

[5] Jochem Struppe et al. J Phys Chem B. (77)Se chemical shift tensor of L-selenocystine: experimental NMR measurements and quantum chemical investigations of structural effects

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Keywords: L-Selenocystine supplier, inhibitors, activators

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