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L-Ribulose

Cat. No. M22481
L-Ribulose Structure
Size Price Availability Quantity
10mg USD 400  USD400 In stock
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Quality Control & Documentation
Biological Activity

L-Ribulose is an important precursor for other rare sugars and L-nucleoside analogue synthesis.

Chemical Information
Molecular Weight 150.13
Formula C5H10O5
CAS Number 2042-27-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Qian Zheng, et al. Appl Biochem Biotechnol. Enhancement of L-ribulose Production from L-ribose Through Modification of Ochrobactrum sp. CSL1 Ribose-5-phosphate Isomerase A

[2] Shahid Mahmood, et al. Food Res Int. A review on l-ribose isomerases for the biocatalytic production of l-ribose and l-ribulose

[3] Jiajun Chen, et al. Appl Microbiol Biotechnol. Recent advances in properties, production, and applications of L-ribulose

[4] Xiaoxiao Liu, et al. J Agric Food Chem. Production of l-Ribulose Using an Encapsulated l-Arabinose Isomerase in Yeast Spores

[5] Litavadee Chuaboon, et al. Angew Chem Int Ed Engl. One-Pot Bioconversion of l-Arabinose to l-Ribulose in an Enzymatic Cascade

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