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L-Glutamine - 13 C 5 is the 13 C-labeled L-Glutamine. L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na + -dependent manner and targets multiple key molecules including glutaminase , mTORC1 , NF-κB , STAT-3 and HIF-1α . L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity .
| Molecular Weight | 151.11 |
| Formula | 13C5H10N2O3 |
| CAS Number | 184161-19-1 |
| Solubility (25°C) | Water: 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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