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L-Citrulline

Cat. No. M19036
L-Citrulline Structure
Size Price Availability Quantity
500mg USD 48  USD48 In stock
1g USD 58  USD58 In stock
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Quality Control & Documentation
Biological Activity

L-Citrulline

Chemical Information
CAS Number 372-75-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Noah M A d'Unienville, et al. J Int Soc Sports Nutr. Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials

[2] Britt Burton-Freeman, et al. Curr Atheroscler Rep. Watermelon and L-Citrulline in Cardio-Metabolic Health: Review of the Evidence 2000-2020

[3] David Khalaf, et al. Nutrients. The Effects of Oral l-Arginine and l-Citrulline Supplementation on Blood Pressure

[4] Arturo Figueroa, et al. Curr Opin Clin Nutr Metab Care. Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance

[5] Luigi Cormio, et al. Urology. Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction

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