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L-798,106

Cat. No. M6889

All AbMole products are for research use only, cannot be used for human consumption.

L-798,106 Structure

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Quality Control & Documentation
Biological Activity

L-798,106 is a potent and highly selective prostanoid EP3 receptor antagonist (Ki values are 0.3, 916, > 5000 and > 5000 nM at EP3, EP4, EP1 and EP2 respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo.

Chemical Information
Molecular Weight 536.44
Formula C27H22BrNO4S
CAS Number 244101-02-8
Solubility (25°C) DMSO 53.64 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Canton, et al. Eur J Pharmacol. Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites.

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Keywords: L-798,106 supplier, inhibitors, activators

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