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KL 001

Cat. No. M6866

All AbMole products are for research use only, cannot be used for human consumption.

KL 001 Structure
Size Price Availability Quantity
5mg USD 100  USD100 In stock
10mg USD 150  USD150 In stock
25mg USD 260  USD260 In stock
50mg USD 400  USD400 In stock
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Quality Control & Documentation
Biological Activity

KL 001 is a first-in-class cryptochrome protein (CRY) stabilizer that interacts specifically with CRY1 and CRY2 to prevent ubiquitin-dependent CRY degradation, thereby prolonging the circadian cycle. In addition, KL001 has the potential to control fasting hormone-induced gluconeogenesis.

Chemical Information
Molecular Weight 398.48
Formula C21H22N2O4S
CAS Number 309928-48-1
Solubility (25°C) DMSO 39.85 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bennett, et al. Mol Pharmacol. Growth hormone secretagogues and growth hormone releasing peptides act as orthosteric super-agonists but not allosteric regulators for activation of the G protein Galpha(o1) by the Ghrelin receptor.

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