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Ketotifen

Cat. No. M29951

All AbMole products are for research use only, cannot be used for human consumption.

Ketotifen Structure
Synonym:

HC 20-511

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Quality Control & Documentation
Biological Activity

Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention.

Chemical Information
Molecular Weight 309.43
Formula C19H19NOS
CAS Number 34580-13-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Axel Karl Gunnar Aberg, et al. Drug Dev Res. Ketotifen is a Prodrug. Norketotifen is the active metabolite

[2] Domenico Italiano, et al. Eur J Pediatr. Ketotifen-induced nocturnal bruxism

[3] G Schwarzer, et al. Cochrane Database Syst Rev. Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children

[4] J O Warner, et al. Clin Allergy. Ketotifen in childhood allergic disease

[5] Y C Govil, et al. Indian Pediatr. Ketotifen

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Keywords: Ketotifen, HC 20-511 supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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