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Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research.
| Molecular Weight | 255.27 |
| Formula | C15H13NO3 |
| CAS Number | 74103-06-3 |
| Solubility (25°C) | DMSO ≥ 110 mg/mL |
| Storage | 4°C, dry, sealed |
[2] Ewan D McNicol, et al. Cochrane Database Syst Rev. Ketorolac for postoperative pain in children
| Related COX Products |
|---|
| Firocoxib
Firocoxib is a selective COX-2 inhibitor exhibiting high selectivity to inhibit COX-2. |
| Ampiroxicam
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound. |
| Bufexamac
Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM. |
| Carprofen
Carprofen inhibits canine COX2 with IC50 of 0.03 mM. |
| Diclofenac Diethylamine
Diclofenac diethylamine is a nonsteroidal anti-inflammatory compound taken to reduce inflammation and as an analgesic reducing pain in certain conditions. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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