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JZP 430

Cat. No. M6860

All AbMole products are for research use only, cannot be used for human consumption.

JZP 430 Structure

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Quality Control & Documentation
Biological Activity

JZP 430 is a potent and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 44 nM). Exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).

Chemical Information
Molecular Weight 354.47
Formula C16H26N4O3S
CAS Number 1672691-74-5
Solubility (25°C) DMSO 17.72 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Engers, et al. J Med Chem. Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs).

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  Catalog
Abmole Inhibitor Catalog




Keywords: JZP 430 supplier, inhibitors, activators

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