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JH-XVI-178 

Cat. No. M29753

All AbMole products are for research use only, cannot be used for human consumption.

JH-XVI-178  Structure

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Quality Control & Documentation
Biological Activity

JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties.

Chemical Information
Molecular Weight 435.91
Formula C22H22ClN7O
CAS Number 2648453-53-4
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] John M Hatcher, et al. ACS Med Chem Lett. Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19

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  Catalog
Abmole Inhibitor Catalog




Keywords: JH-XVI-178  supplier, CDK, inhibitors, activators

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