Free shipping on all orders over $ 500

Itaconate-alkyne

Cat. No. M43962

All AbMole products are for research use only, cannot be used for human consumption.

Itaconate-alkyne Structure
Synonym:

ITalk

Size Price Availability Quantity
10mg USD 320  USD320 In stock
25mg USD 640  USD640 In stock
50mg USD 920  USD920 In stock
100mg USD 1280  USD1280 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Itaconate-alkyne is a specific bioorthogonal probe and functional analog of Itaconation, which has similar anti-inflammatory activity to Itaconic acid, and can label the true target of Itaconic acid for quantitative and localized Itaconic acid chemistry proteomics analysis in living cells. In addition, Itaconate-alkyne is also a click chemistry containing an Alkyne moiety that undergoes a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide moiety.

Chemical Information
Molecular Weight 238.28
Formula C13H18O4
CAS Number 2454181-83-8
Form Solid
Solubility (25°C) DMSO >100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chao Wei, et al. Cell Death Differ. Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke

[2] Wei Qin, et al. J Am Chem Soc. Chemoproteomic Profiling of Itaconation by Bioorthogonal Probes in Inflammatory Macrophages

Related Products
2-Deoxy-2-fluoro-D-glucose

2-Deoxy-2-fluoro-D-glucose is a radiolabeled glucose analog, which is commonly used in medical imaging techniques such as positron emission tomography (PET) scans.

2-Bromo-4-chlorophenylacetic acid

2-Bromo-4-chlorophenylacetic acid is a biochemical reagent.

CPN-351 TFA

CPN-351 TFA is a selective pentapeptide antagonist of human NMUR1 with a pA2 of 7.35. CPN-351 TFA can be used for the research of inflammation.

5-Phenyluracil

5-Phenyluracil is a pyrimidine derivative, a class of heterocyclic aromatic organic compounds crucial in biochemistry. It serves as a synthetic nucleoside analogue, meaning it mimics the structure of naturally occurring nucleosides like uridine. This structural similarity allows it to participate in biochemical reactions, often interfering with normal cellular processes, making it a valuable tool in studying nucleic acid metabolism and developing antiviral and anticancer agents.

7-Deoxyloganin

7-Deoxyloganin is a biosynthetic precursor of Loganin. 7-Deoxyloganin undergoes hydroxylation catalyzed by 7-deoxyloganin 7-hydroxylase, a cytochrome P450-dependent monooxygenase, to produce Loganin.

  Catalog
Abmole Inhibitor Catalog




Keywords: Itaconate-alkyne, ITalk supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.