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Isoallolithocholic acid

Cat. No. M39732

All AbMole products are for research use only, cannot be used for human consumption.

Isoallolithocholic acid Structure
Synonym:

3β-Hydroxy-5α-cholanic acid

Size Price Availability Quantity
1mg USD 109  USD109 In stock
5mg USD 240  USD240 In stock
10mg USD 380  USD380 In stock
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Quality Control & Documentation
Biological Activity

Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid, is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation.

Chemical Information
Molecular Weight 376.57
Formula C24H40O3
CAS Number 2276-93-9
Form Solid
Solubility (25°C) DMSO 83 mg/mL (ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tahrir Alenezi et al. Pathogens. Potent Bile Acid Microbial Metabolites Modulate Clostridium perfringens Virulence

[2] Tadashi Fujii et al. J Nutr Sci Vitaminol (Tokyo). 1-Kestose Supplementation Increases Levels of a 5α-Reductase Gene, a Key Isoallolithocholic Acid Biosynthetic Gene, in the Intestinal Microbiota

[3] Wei Li et al. Cell Host Microbe. A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1

[4] Yuko Sato et al. Nature. Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

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Keywords: Isoallolithocholic acid, 3β-Hydroxy-5α-cholanic acid supplier, inhibitors, activators

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