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IL-17 modulator 1 is an orally active, highly efficacious small molecule IL-17 modulator. IL-17 modulator 1 can be used for the research of preventing, researching or ameliorating a variety of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis.
| Molecular Weight | 584.6 |
| Formula | C28H37N6O6P |
| CAS Number | 2446803-85-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Donggi Paik, et al. Nature. Human gut bacteria produce ΤΗ17-modulating bile acid metabolites
[3] Ritesh Kumar, et al. Trends Immunol. RORγt protein modifications and IL-17-mediated inflammation
[5] Eric V Dang, et al. Cell. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1
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Perfluorodecanoic acid (PFDA) is widely used as surfactants, polymer and plastic additives, wetting agents, corrosion inhibitors, lubricants, foam-fire extinguishants, etc. Perfluorodecanoic acid induces weight loss and increases liver weight and lipid content in mice. Perfluorodecanoic acid also reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver. |
| IL-15-IN-1
IL-15-IN-1 is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM. |
| IL-17 modulator 3
IL-17 modulator 3 is an IL-17 modulator. |
| IL-17 modulator 4
IL-17 modulator 4 is a proagent of IL-17 modulator 1. |
| IL-17A modulator-3
IL-17A modulator-3 is a IL-17A modulator. |
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