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ICI 199441

Cat. No. M27855

All AbMole products are for research use only, cannot be used for human consumption.

ICI 199441 Structure

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Quality Control & Documentation

Purity: ≥99.0%
COA
MSDS

Product Information

Biological Activity

ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion.

Chemical Information

Molecular Weight	427.8
Formula	C21H25Cl3N2O
CAS Number	115199-84-3
Form	Solid
Solubility (25°C)	DMSO 250 mg/mL (ultrasonic)
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Yi-Min Tao, et al. Eur J Pharmacol. LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential

[2] Amanda J Page, et al. Am J Physiol Gastrointest Liver Physiol. Opioid modulation of ferret vagal afferent mechanosensitivity

[3] Jolan M Terner, et al. Behav Pharmacol. Effects of the long-lasting kappa opioid 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl) ethyl] acetamide in a drυg discrimination and warm water tail-withdrawal procedure

[4] Tomohisa Mori, et al. Life Sci. Differential properties between TRK-820 and U-50,488H on the discriminative stimulus effects in rats

[5] T Endoh, et al. Eur J Pharmacol. Characterization of the antinociceptive effects of TRK-820 in the rat

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Catalog

Abmole Inhibitor Catalog

Keywords: ICI 199441 supplier, Opioid Receptor, inhibitors, activators

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