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ICG-OSu

Cat. No. M21459
ICG-OSu Structure
Synonym:

ICG NHS ester

Size Price Availability Quantity
5mg USD 510  USD510 In stock
10mg USD 820  USD820 In stock
25mg USD 1650  USD1650 In stock
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Quality Control
  • Current batch:
  • Purity >97%
  • COA
  • MSDS
Biological Activity

ICG-OSu (ICG NHS ester) is a near infrared fluorescent agent with amine reactivity that is widely used in the design of in vivo imaging probes. Em >750 nm infrared, Ex >750 nm infrared.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 828.04
Formula C49H53N3O7S
CAS Number 1622335-40-3
Purity >97%
Solubility DMSO : 25 mg/mL
Storage -20℃, protect from light, dry, sealed
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Keywords: ICG-OSu, ICG NHS ester supplier, Fluorescent Dye, inhibitors

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