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IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research.
| Molecular Weight | 599.02 |
| CAS Number | 1807523-99-4 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage | 2-8°C, dry, sealed |
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