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I-BET567 

Cat. No. M28993

All AbMole products are for research use only, cannot be used for human consumption.

I-BET567  Structure

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Quality Control & Documentation
Biological Activity

I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammation.

Chemical Information
Molecular Weight 359.81
Formula C17H18ClN5O2
CAS Number 1887237-54-8
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage 4°C, protect from light
References

[1] Philip G Humphreys, et al. J Med Chem. Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate

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  Catalog
Abmole Inhibitor Catalog




Keywords: I-BET567  supplier, Epigenetic Reader Domain, inhibitors, activators

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