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hFSH-β-(33-53) TFA

Cat. No. M54736
hFSH-β-(33-53) TFA Structure

hFSH beta-(33-53) TFA

Size Price Availability Quantity
10mg USD 230  USD230 In stock
25mg USD 450  USD450 In stock
50mg USD 700  USD700 In stock
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Quality Control & Documentation
Biological Activity

hFSH-β-(33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a FSHR (follicle-stimulating hormone receptor) antagonist. hFSH-β-(33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells.


Chemical Information
Formula C115H183N31O32S.x(C2HF3O2)
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Storage Store at ≤ -20°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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Keywords: hFSH-β-(33-53) TFA, hFSH beta-(33-53) TFA supplier, Estrogen Receptor, inhibitors, activators

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