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HEPES

Cat. No. M6793
HEPES Structure
Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
50g USD 70  USD70 In stock
100g USD 120  USD120 In stock
250g USD 220  USD220 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

HEPES is a multi purpose buffer used in biological research.

Product Citations
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 238.3
Formula C8H18N2O4S
CAS Number 7365-45-9
Purity >99%
Solubility Water ≥ 200 mg/mL
Storage at -20°C
References

[1] Pierce, et al. J Med Chem. Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: HEPES supplier, inhibitors

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