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Hematin, an iron-containing porphyrin, inhibits the activity of clotting factors and also fibrin clot lysis through the mechanism of binding to and inactivation of hemostatic proteins. Hematin can be used for the research of acute porphyrias and cancer.
| Molecular Weight | 633.49 |
| Formula | C34H33FeN4O5 |
| CAS Number | 15489-90-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 1.43 mg/mL (ultrasonic and warming and heat to 70°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] J W DANIEL, et al. J Bacteriol. Hematin--requiring plasmodial myxomycete
[3] G Blauer, et al. Biochem Mol Biol Int. B-hematin
[4] C A Pierach. Semin Liver Dis. Hematin therapy for the porphyric attack
[5] D Green, et al. J Lab Clin Med. Hematin: effects on hemostasis
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