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H3B-5942 is a selective and irreversible estrogen receptor covalent antagonist, inactivates both ERα WT and ERα mutation. The Ki values are 1 nM and 0.41 nM, respectively.
| Molecular Weight | 494.63 |
| Formula | C31H34N4O2 |
| CAS Number | 2052128-15-9 |
| Solubility (25°C) | DMSO 99 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Craig Furman, et al. Cancer Res. Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come
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