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GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.
| Molecular Weight | 510.58 |
| CAS Number | 1936421-41-8 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, sealed |
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