Free shipping on all orders over $ 500

Ghrelin (human) Acetate

Cat. No. M10340
Ghrelin (human) Acetate Structure
Synonym:

HuGHRL Acetate

Size Price Availability Quantity
1mg USD 300  USD300 In stock
5mg USD 600  USD600 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Ghrelin (human) Acetate is an endogenous agonist peptide for the ghrelin (GHS) receptor. Ghrelin (human) Acetate stimulates release of growth hormone from the pituitary gland and regulates feeding, appetite, growth and energy homeostasis.

Chemical Information
CAS Number 258279-04-8 (free base)
Solubility (25°C) Soluble in water
Storage -20°C, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Tiziana Napolitano, et al. Diabetes Obes Metab. Role of ghrelin in pancreatic development and function

[2] Shigehisa Yanagi, et al. Cell Metab. The Homeostatic Force of Ghrelin

[3] Mahalaqua Nazli Khatib, et al. Cochrane Database Syst Rev. Ghrelin for the management of cachexia associated with cancer

[4] Laura M Frago, et al. Int J Mol Sci. Involvement of Astrocytes in Mediating the Central Effects of Ghrelin

[5] Ken Howick, et al. Int J Mol Sci. From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

[6] Yuanjie Mao, et al. Hypertension. Ghrelin as a treatment for cardiovascular diseases

[7] Katsuya Dezaki, et al. Pharmacol Ther. Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis

Related Peptides Products
Trypsin Inhibitor (from Soybean)

Trypsin inhibitor is an alkaline polypeptide consisting of 58 amino acid residues with a pear shape throughout the molecule and a lysine activity center. It can compete with the activity center of many proteases for a lysyl group and inhibit their activities.

(D-His2,D-Trp6)-LHRH

(D-His2,D-Trp6)-LHRH is a peptide that can be discovered by peptide screening. Peptide screening is a research tool that assembles active peptides primarily by immunoassay. It can be used for protein interactions, functional analysis, antigenic epitope screening, and the development and study of active molecules.

Ghrelin (mouse, rat) TFA

Ghrelin (mouse, rat) TFA is a gastrointestinal secretory-generated, endogenous brain-gut peptide consisting of 28 amino acids that possesses a variety of physiological functions including appetite stimulation, and is also an endogenous agonist peptide for the ghrelin (GHS) receptor.

LIP1 (human)

LIP1 (human) is a polypeptide produced from the anterior region of nerve growth factor (NGF) containing 29 amino acids that induces F-actin rearrangement, phosphorylates TrkA and Akt, and has antiproliferative as well as neuroprotective activities. Sequence: ARSAPAAAIAARVAGQTRNITVDPRLFKK

Kisspeptin-10, human ACETATE

Kisspeptin-10, human ACETATE is the acetate form of Kisspeptin-10 and is also a potent vasoconstrictor and angiogenesis inhibitor that inhibits tumor metastasis through its receptor GPR54.Kisspeptin-10/GPR54 signaling through NFATc4-mediated BMP2 expression to induces osteoblast differentiation through NFATc4-mediated BMP2 expression.

  Catalog
Abmole Inhibitor Catalog




Keywords: Ghrelin (human) Acetate, HuGHRL Acetate supplier, Peptides, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.