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Ghrelin (human) Acetate

Cat. No. M10340
Ghrelin (human) Acetate Structure

HuGHRL Acetate

Size Price Availability Quantity
1mg USD 300  USD300 In stock
5mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

Ghrelin (human) Acetate is an endogenous agonist peptide for the ghrelin (GHS) receptor. Ghrelin (human) Acetate stimulates release of growth hormone from the pituitary gland and regulates feeding, appetite, growth and energy homeostasis.

Chemical Information
CAS Number 258279-04-8 (free base)
Solubility (25°C) Soluble in water
Storage -20°C, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Tiziana Napolitano, et al. Diabetes Obes Metab. Role of ghrelin in pancreatic development and function

[2] Shigehisa Yanagi, et al. Cell Metab. The Homeostatic Force of Ghrelin

[3] Mahalaqua Nazli Khatib, et al. Cochrane Database Syst Rev. Ghrelin for the management of cachexia associated with cancer

[4] Laura M Frago, et al. Int J Mol Sci. Involvement of Astrocytes in Mediating the Central Effects of Ghrelin

[5] Ken Howick, et al. Int J Mol Sci. From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

[6] Yuanjie Mao, et al. Hypertension. Ghrelin as a treatment for cardiovascular diseases

[7] Katsuya Dezaki, et al. Pharmacol Ther. Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis

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Keywords: Ghrelin (human) Acetate, HuGHRL Acetate supplier, Peptides, inhibitors, activators

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