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Gefitinib impurity 1

Cat. No. M39071

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Gefitinib impurity 1 Structure

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Quality Control & Documentation
Biological Activity

Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM).

Chemical Information
Molecular Weight 321.33
Formula C15H19N3O5
CAS Number 675126-26-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chunyan Sun et al. Se Pu. [A high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of four genotoxic impurities in gefitinib]

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