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Gefitinib HCl

Cat. No. M5679

All AbMole products are for research use only, cannot be used for human consumption.

Gefitinib HCl Structure
Synonym:

ZD-1839 hydrochloride

Size Price Availability
100mg USD 60  USD60 1-2 Weeks
500mg USD 105  USD105 1-2 Weeks
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Quality Control & Documentation
Biological Activity

Gefitinib Hcl(ZD-1839 Hcl) is an EGFR inhibitor, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR.

Chemical Information
Molecular Weight 483.36
Formula C22H25Cl2FN4O3
CAS Number 184475-55-6
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Burotto M, et al. Oncologist. Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials.

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Keywords: Gefitinib HCl, ZD-1839 hydrochloride supplier, EGFR/HER2, inhibitors, activators

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