Free shipping on all orders over $ 500

G-9791 

Cat. No. M29025

All AbMole products are for research use only, cannot be used for human consumption.

G-9791  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

G-9791, a poyridone side chain analogue, is a potent PAK inhibitor with Ki values of 0.95 nM and 2.0 nM for PAK1 and PAK2, respectively.

Chemical Information
Molecular Weight 508.98
Formula C26H26ClFN6O2
CAS Number 1926204-95-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Joachim Rudolph, et al. J Med Chem. Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Related PAK Products
st-Ht31

st-Ht31 is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring.

AZA197

AZA197 is a selective small molecule inhibitor of Cdc42.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro.

ZMF-23

ZMF-23 is a PAK1/HDAC6 dual inhibitor.

PF-3758309 dihydrochloride

PF-3758309 (PF-03758309) dihydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation.

AZ13705339 hemihydrate 

AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers.

  Catalog
Abmole Inhibitor Catalog




Keywords: G-9791  supplier, PAK, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.