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G-36 is a antagonist of GPER; selectively inhibits estrogen-mediated activation of PI3-K by GPER, but not by ERα. Also inhibits estrogen-mediated calcium mobilization (IC50 = 112 nM). Structural analog of G-1.
| Molecular Weight | 412.33 |
| Formula | C22H22BrNO2 |
| CAS Number | 1392487-51-2 |
| Solubility (25°C) | DMSO 41.23 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Battey and Wada. TiNS. Two distinct subtypes for mammalian bombesin-like peptides.
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