Free shipping on all orders over $ 500

FLTX1

Cat. No. M45333

All AbMole products are for research use only, cannot be used for human consumption.

FLTX1 Structure
Size Price Availability Quantity
1mg USD 120  USD120 In stock
5mg USD 270  USD270 In stock
10mg USD 420  USD420 In stock
25mg USD 720  USD720 In stock
50mg USD 980  USD980 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

FLTX1 is a fluorescent tamoxifen derivative that specifically labels intracellular tamoxifen binding sites (estrogen receptors) under permeabilizing and non-permeabilizing conditions. In addition, FLTX1 exhibits potent anti-estrogenic activity of Tamoxifen in breast cancer cells.FLTX1 lacks estrogenic agonism in the uterus.

Chemical Information
Molecular Weight 520.58
Formula C31H28N4O4
CAS Number 1481401-71-1
Form Solid
Solubility (25°C) DMSO 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mario Díaz, et al. Int J Mol Sci. FLTX2: A Novel Tamoxifen Derivative Endowed with Antiestrogenic, Fluorescent, and Photosensitizer Properties

[2] F Lahoz, et al. Spectrochim Acta A Mol Biomol Spectrosc. FRET mechanism between a fluorescent breast-cancer drug and photodynamic therapy sensitizers

[3] Araceli Morales, et al. Methods Mol Biol. Colocalization of Estrogen Receptors with the Fluorescent Tamoxifen Derivative, FLTX1, Analyzed by Confocal Microscopy

[4] Jorge Marrero-Alonso, et al. Eur J Pharm Biopharm. Unique SERM-like properties of the novel fluorescent tamoxifen derivative FLTX1

Related Estrogen Receptor Products
GDC-0927

GDC-0927 (SRN-927) is a novel, potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist.

AC-186 

AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively.

Idoxifene

Idoxifene (CB7432) is a novel tissue-specific selective estrogen receptor modulator (SERM).

(R)-Equol

(R)-Equol is an agonist of both ERα and ERβ with Kis of 27.4 and 15.4 nM, respectively.

(Rac)-Vepdegestrant

(Rac)-Vepdegestrant is the isomer of Vepdegestrant.

  Catalog
Abmole Inhibitor Catalog




Keywords: FLTX1 supplier, Estrogen Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.