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FF-10502 

Cat. No. M28944

All AbMole products are for research use only, cannot be used for human consumption.

FF-10502  Structure

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Quality Control & Documentation
Biological Activity

FF-10502, a structural analog of Gemcitabine, is a pyrimidine nucleoside antimetabolite. FF-10502 inhibits DNA polymerase α and β. FF-10502 shows beneficial anticancer activity via a mechanism of action on dormant cells.

Chemical Information
Molecular Weight 261.27
Formula C9H12FN3O3S
CAS Number 184302-49-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Filip Janku, et al. Cancer. A phase 1/2a safety, pharmacokinetics, and efficacy study of the novel nucleoside analog FF-10502-01 for the treatment of advanced solid tumors

[2] Shinji Mima, et al. J Pharmacol Exp Ther. FF-10502, an Antimetabolite with Novel Activity on Dormant Cells, Is Superior to Gemcitabine for Targeting Pancreatic Cancer Cells

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N1-Methylpseudouridine

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Diguanosine 5′-triphosphate

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  Catalog
Abmole Inhibitor Catalog




Keywords: FF-10502  supplier, Nucleoside Antimetabolite/Analog, inhibitors, activators

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