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EPO mimetic peptide-1

Cat. No. M43916

All AbMole products are for research use only, cannot be used for human consumption.

EPO mimetic peptide-1 Structure
Synonym:

EMP-1

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Quality Control & Documentation
Biological Activity

EPO mimetic peptide-1 (EMP-1) is a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation, affects cell cycle and induces the production of reticulocytes in vivo. EPO mimetic peptide-1 (1 and 10 μM) promots erythroid colony formation from human peripheral blood and murine bone marrow. EPO mimetic peptide-1 affects cell cycle.

Sequence: GGTYSCHFGPLTWVCKPQGG

Chemical Information
Molecular Weight 2095.36
Formula C94H135N25O26S2
CAS Number 186526-28-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Neeraj Agarwal, et al. Semin Hematol. Erythropoietic agents and the elderly

[2] F P Barbone, et al. Nephrol Dial Transplant. New epoetin molecules and novel therapeutic approaches

[3] S A Middleton, et al. J Biol Chem. Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide

[4] D L Johnson, et al. Biochemistry. Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1

[5] O Livnah, et al. Science. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

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Keywords: EPO mimetic peptide-1, EMP-1 supplier, inhibitors, activators

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