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Emibetuzumab

Cat. No. M24631

All AbMole products are for research use only, cannot be used for human consumption.

Emibetuzumab Structure
Synonym:

LY2875358

Price and Availability

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Quality Control & Documentation
Biological Activity

Emibetuzumab (LY2875358) is a humanized bivalent MET antibody (IgG4 type). Emibetuzumab shows high neutralization and internalization activities, resulting in inhibition of both HGF-dependent and HGF-independent MET pathway activation and tumor growth. Emibetuzumab can be used in study of cancer.

Chemical Information
CAS Number 1365287-97-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] S Betty Yan, et al. Invest New Drugs. MET-targeting antibody (emibetuzumab) and kinase inhibitor (merestinib) as single agent or in combination in a cancer model bearing MET exon 14 skipping

[2] Lee S Rosen, et al. Clin Cancer Res. A First-in-Human Phase I Study of a Bivalent MET Antibody, Emibetuzumab (LY2875358), as Monotherapy and in Combination with Erlotinib in Advanced Cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: Emibetuzumab, LY2875358 supplier, c-Met, inhibitors, activators

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