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Eicosapentaenoic Acid

Cat. No. M21265
Eicosapentaenoic Acid Structure
Synonym:

EPA; Timnodonic acid

Size Price Availability Quantity
50mg USD 48  USD60 In stock
100mg USD 65.6  USD82 In stock
500mg USD 268  USD335 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation.Nutritional supplement in health care products.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 302.45
Formula C20H30O2
CAS Number 10417-94-4
Purity >99%
Solubility DMSO : ≥ 53 mg/mL
Storage -20°C
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Keywords: Eicosapentaenoic Acid, EPA; Timnodonic acid supplier, Endogenous Metabolite, inhibitors

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