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ECBN biosynthesis cluster Ani in the genome of the echinocandin B producer strain A. nidulans NRRL 8112. ECBN belongs to lipopeptide antifungal antibiotic bearing five types of direct precursor amino acids including proline, ornithine, tyrosine, threonine, and leucine. ECBN obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-d-glucan synthase.
Molecular Weight | 834.27 |
Formula | C34H51N7O15.HCl |
CAS Number | 1029890-89-8 |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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