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EB 47

Cat. No. M6696

All AbMole products are for research use only, cannot be used for human consumption.

EB 47 Structure

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Quality Control & Documentation
Biological Activity

EB 47 is a potent inhibitor of PARP-1 (IC50 = 45 nM). Reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model.

Chemical Information
Molecular Weight 610.45
Formula C24H27N9O6.2HCl
CAS Number 1190332-25-2
Solubility (25°C) Water 3.05 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Balakrishnan, et al. J Biol Chem. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium.

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Abmole Inhibitor Catalog




Keywords: EB 47 supplier, inhibitors, activators

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