Free shipping on all orders over $ 500

DZD1516

Cat. No. M40621

All AbMole products are for research use only, cannot be used for human consumption.

DZD1516 Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

DZD1516 is an orally active, potent, reversible, and selective HER2 small molecule tyrosine kinase inhibitors (TKIs) with an IC50 value of 0.56 nM, which completely penetrates the blood-brain barrier. It can be used in studies related to HER2-positive breast cancer.

Chemical Information
Molecular Weight 547.56
Formula C28H27F2N7O3
CAS Number 2387570-00-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jian Zhang et al. Breast Cancer Res. Preclinical and clinical activity of DZD1516, a full blood-brain barrier-penetrant, highly selective HER2 inhibitor

Related EGFR/HER2 Products
Sevabertinib

Sevabertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with antitumor activity.

BPIQ-I

BPIQ-I (PD 159121) is a potent and ATP-competitive EGFR tyrosine kinase inhibitor..

HKI-357 

HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively.

SJF-1528 

SJF-1528 is a potent EGFR PROTAC degrader with DC50 values of 39.2 nM and 736.2 nM for wild-type EGFR in OVCAR8 cells and Exon 20 Ins mutated EGFR in HeLa cells.

CH7233163 

CH7233163 is a noncovalent ATP-competitive inhibitor for EGFR-Del19/T790M/C797S.

  Catalog
Abmole Inhibitor Catalog




Keywords: DZD1516 supplier, EGFR/HER2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.