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DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles.
| Formula | (C2H4O)nC32H62O5 |
| CAS Number | 160743-62-4 |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic and warming) Ethanol 90 mg/mL (Need ultrasonic) Water 15 mg/mL (Need ultrasonic) |
| Storage | -20°C, protect from light, dry, sealed |
[4] S Moein Moghimi. Mol Ther. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines
[5] Weiyu Zhao, et al. Cell Mol Bioeng. Lipid Polymer Hybrid Nanomaterials for mRNA Delivery
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| DOTAP methylsulfate
DOTAP methylsulfate is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. |
| Chitosan (MW 150000)
Chitosan (MW 150000) is a polycationic linear polysaccharide derived from chitin with a molecular weight of 150000.Chitosan is non-toxic, hypoallergenic, biocompatible, biodegradable, and possesses anti-tumor, anti-bacterial, anti-fungal, and anti-oxidant activities.Chitosan can be used in studies related to drug delivery and cell transfection. |
| Chitosan (MW 30000)
Chitosan (MW 30000) is a polycationic linear polysaccharide derived from chitin with a molecular weight of 30,000.Chitosan is non-toxic, hypoallergenic, biocompatible, biodegradable, and possesses anti-tumor, anti-bacterial, anti-fungal, and antioxidant activities.Chitosan can be used in studies related to drug delivery and cell transfection. |
| DMTAP
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs. |
| Polyethylenimine, Linear (MW 25000)
Polyethylenimine Linear (PEI) solution consists of a cationic polymer transfection reagent with a molecular weight of 25,000, which forms a complex with nucleic acids and allows the complex to enter mammalian cells. In addition, Polyethylenimine Linear is one of the most commonly used reagents in small to large scale transfection. |
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