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DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.
| Molecular Weight | 135.19 |
| Formula | C4H9NO2S |
| CAS Number | 454-29-5 |
| Form | Solid |
| Solubility (25°C) | Water 40 mg/mL |
| Storage | Powder -20°C |
| Related Metabolite/Endogenous Metabolite Products |
|---|
| p-Cresol glucuronide
p-Cresol glucuronide is a metabolite of p-cresol, it is a prototype protein-bound uremic toxin. |
| Oleamide
Oleamide is an endogenous fatty acid amide. |
| Deoxycarnitine chloride
Deoxycarnitine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota. |
| Monobutyl phthalate
Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. |
| Testosterone sulfate (pyridinium)
Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone. |
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